C57BL/6 - Wikipedia
WEBC57BL/6, often referred to as "C57 black 6", "B6", "C57" or "black 6", is a common inbred strain of laboratory mouse. It is the most widely used "genetic background" for genetically modified mice for use as models of human disease.
000664 - B6 Strain Details - The Jackson Laboratory
WEBAlthough this strain is refractory to many tumors, it is a permissive background for maximal expression of most mutations. C57BL/6J mice are resistant to audiogenic seizures, have a relatively low bone density, and develop age related hearing loss.
The History of Black 6 Mice | Charles River Laboratories
WEBThis blog examines how Black 6 (B6) mice have aided a century of basic research and drug discovery.
All Black 6 mice are not created equal - The Jackson Laboratory
WEBRecent papers describe genetic and phenotypic differences between the two most common “Black 6” substrains – C57BL/6J and C57BL/6N.
Aged C57BL/6J Mice - The Jackson Laboratory
WEBAged C57BL/6J mice have research applications that include immunology, cancer, longevity interventions, and biomarker studies. C57BL/6J is the most widely used inbred mouse strain and the first to have its genome sequenced.
C57BL 6 Mouse - an overview | ScienceDirect Topics
WEBThe C57BL6, often referred to as C57 black 6, is among the most commonly used laboratory mice [15]. It is the popular genetic background for GEMM (genetically modified mice) used for modeling human disease (genetic mice models are covered in another chapter of this book).
Protect Your Research: Know Your B6 Mouse - The Jackson …
WEBApr 13, 2020 · The C57BL/6 inbred mouse (B6) is the most commonly used research strain. This strain is the most well characterized, the first to have its’ entire genome sequenced, and is the genetic background strain of …
Experiments done in Black-6 mice: what does it mean? | Lab …
WEBApr 22, 2019 · Attempts to enhance the replicability and to reduce the variability in basic research has led to the recommendation to use isogenic mice. The C57BL/6 strain has evolved as a gold standard strain...
Experiments done in Black-6 mice: what does it mean? - PubMed
WEBLow replicability of animal experiments is perceived as a major hurdle in the field of biomedicine. Attempts to enhance the replicability and to reduce the variability in basic research has led to the recommendation to use isogenic mice.
The C57BL/6 mouse (1921) | British Society for Immunology
WEBPerhaps no strain of mouse exemplifies this best than a highly inbred mouse strain known as C57BL/6, sometimes abbreviated to “black 6” or B6. This dark-furred rodent is sensitive to pain and cold, likes to drink alcohol when offered it, and tends to suffer from atherosclerosis and age-related hearing loss.